Rory Sutherland is among four players to be called into Scotland's Six Nations squad ahead of Saturday's encounter against Italy in Rome.
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Sutherland is joined by fellow prop Javan Sebastian plus back Jamie Dobie and flanker Marshall Sykes, who made one previous appearance, in 2021.
Sione Tuipulotu, Alex Craig and WP Nel have dropped out of Gregor Townsend's squad.
The match comes as Italy's English-born back row Jake Polledri announced his retirement, aged 28, primarily due to injury issues suffered in the same clash four years ago.
Polledri said he had never fully recovered from a serious injury suffered four years ago.
The flanker suffered a broken leg as well as knee, hamstring and calf injuries in a 2020 match against Scotland.
Sidelined for two years Polledri returned to represent Italy in the Six Nations but further injuries curtailed a promising career.
My foot however hasn't returned back to 100% and ultimately it has affected my ability to return to the high level of rugby I played, and it has also affected life generally," Polledri said on Instagram.
"I have reluctantly accepted that my body and professionals are telling me retire from the sport that I love."
Australian Associated Press
